Via jobs.ac.uk. 'Epigenetic Programming And Expression Of Leptin During The Life Cycle: Developmental And Environmental Influences'; a PhD studentship offered by the School of Biosciences - Division of Animal Sciences, University of Nottingham. Epigenetic mechanisms mediate gene-environment interactions and can affect energy balance. Leptin is one of the important hormones that regulate weight and appetite. The successful student will explore epigenetic mechanisms that govern the dynamics of Leptin expression during the mammalian life cycle. The project will examine whether environmental stressors (dietary or hormonal) imposed during certain periods of development induce lasting epigenetic variation at the Leptin locus. Such epigenetic variation could influence the adult phenotype, including the wiring of neurons that regulate feeding behaviour. Ambitious students who are committed to science and hard working are encouraged to apply.

This project will utilise current techniques in molecular biology, cell biology and biochemistry that are relevant for this exciting new field of research. The facilities and the scientific expertise in the Division of Animal Sciences and on campus offer excellent conditions and throughout the course of the studentship you will experience a rich and collegial scientific atmosphere. You will be exposed to a broad range of topics related to the project, such as organismal biology, physiology, ethical issues, statistical analyses, epidemiology, and mathematical modeling. Students should have a minimum of a 2(i) in a relevant discipline. This studentship is available for a period of three years from October 2009 and only provides funding for Home/EU students (UK/EU citizens resident in the UK), due to funding restrictions. Informal enquiries may be addressed to biosciences-pg-admissions@Nottingham.ac.uk.

Job advert